Looking for the best gluten-free meatloaf recipe that’s both flavorful and simple to make? This juicy meatloaf is made with lean ground beef, gluten-free breadcrumbs, and a rich, tangy glaze of ketchup, brown sugar, and Dijon mustard. Perfect for weeknight dinners or meal prep, this hearty dish is baked to perfection and pairs beautifully with classic sides like mashed potatoes and steamed vegetables. Whether you’re gluten-intolerant or just exploring gluten-free meals, this easy meatloaf recipe is a must-try for a satisfying and wholesome dinner.

Ingredients:
For the Meatloaf:
- 2 pounds lean ground beef (85/15 or 90/10 recommended)
- ½ cup diced white onion
- 2 large eggs
- 1 cup gluten-free breadcrumbs
- 2 cloves garlic, minced
- ¼ cup milk of choice (whole, 2%, almond, etc.)
- 2 teaspoons salt (adjust to taste)
- ½ teaspoon freshly ground black pepper (adjust to taste)
For the Glaze:
- ½ cup ketchup
- 2 tablespoons packed light brown sugar
- 1 teaspoon Dijon mustard
Instructions:
Prepare the Meatloaf:
- Preheat your oven to 350°F (175°C). Line a large baking sheet with aluminum foil and set it aside.
- In a large mixing bowl, combine the ground beef, diced onion, eggs, gluten-free breadcrumbs, minced garlic, milk, salt, and pepper. Use your hands to mix the ingredients until fully incorporated.
- Transfer the mixture to the prepared baking sheet and shape it into a loaf approximately 8 inches long and 4 inches wide. Set aside.
Prepare the Glaze:
4. In a small mixing bowl, whisk together the ketchup, light brown sugar, and Dijon mustard until smooth and fully combined.
5. Brush or pour the glaze over the top and sides of the meatloaf, ensuring it is evenly coated.
Bake the Meatloaf:
6. Place the baking sheet in the preheated oven and bake for 1 hour. Begin checking the internal temperature using a meat thermometer after the first hour.
7. Continue baking as needed, checking every 5 to 10 minutes, until the internal temperature reaches 155°F (68°C).
8. Once cooked, carefully remove the meatloaf from the oven and let it rest for 5 minutes on the baking sheet.
9. Slice the meatloaf into 8 even portions and serve with your favorite sides.
Why You’ll Love This Recipe
This Gluten-Free Meatloaf is a classic comfort food made accessible for those with gluten sensitivities. It’s moist, flavorful, and has a perfectly tangy glaze that everyone will love. Made with simple ingredients and no complicated steps, it’s a family-friendly dish that’s both easy to prepare and packed with wholesome flavor.

Tips
- Use lean ground beef for the best balance between flavor and texture. Ground beef with too much fat may make the loaf greasy.
- Don’t overmix the meat mixture, as this can result in a dense meatloaf. Mix just until the ingredients are combined.
- Use a meat thermometer to ensure the perfect doneness without overcooking.
- Let the meatloaf rest for 5 minutes before slicing to help retain its juices.
Variations and Substitutions
- Protein swap: Substitute ground beef with ground turkey or chicken for a lighter version.
- Breadcrumb alternatives: Use crushed gluten-free crackers or rolled oats if you don’t have breadcrumbs on hand.
- Add veggies: Mix in grated carrots, zucchini, or chopped mushrooms for added nutrients.
- Make it dairy-free: Use unsweetened almond milk or another non-dairy milk option.
FAQs
Can I make this meatloaf ahead of time?
Yes! You can assemble the meatloaf and store it in the fridge for up to 24 hours before baking. Cover it tightly to prevent drying out.
Can I freeze meatloaf?
Absolutely! Wrap the uncooked loaf tightly in plastic wrap and aluminum foil, then freeze for up to 3 months. Thaw in the refrigerator overnight before baking.
What’s the best way to reheat meatloaf?
Reheat slices in a 350°F oven for 10-15 minutes or microwave them in 30-second intervals until warmed through.
Serving Suggestions
This gluten-free meatloaf pairs beautifully with classic sides like:
- Mashed potatoes
- Roasted or steamed vegetables
- A fresh green salad
- Gluten-free dinner rolls
For a complete comfort meal, drizzle the meatloaf slices with extra glaze or serve with a rich gravy. Enjoy!
Gluten-Free Meatloaf
8
servings15
minutes1
hour30
minutesIngredients
For the Meatloaf:
2 pounds lean ground beef (85/15 or 90/10 recommended)
½ cup diced white onion
2 large eggs
1 cup gluten-free breadcrumbs
2 cloves garlic, minced
¼ cup milk of choice (whole, 2%, almond, etc.)
2 teaspoons salt (adjust to taste)
½ teaspoon freshly ground black pepper (adjust to taste)
For the Glaze:
½ cup ketchup
2 tablespoons packed light brown sugar
1 teaspoon Dijon mustard
Directions
- Prepare the Meatloaf:
- Preheat your oven to 350°F (175°C). Line a large baking sheet with aluminum foil and set it aside.
- In a large mixing bowl, combine the ground beef, diced onion, eggs, gluten-free breadcrumbs, minced garlic, milk, salt, and pepper. Use your hands to mix the ingredients until fully incorporated.
- Transfer the mixture to the prepared baking sheet and shape it into a loaf approximately 8 inches long and 4 inches wide. Set aside.
- Prepare the Glaze:
- In a small mixing bowl, whisk together the ketchup, light brown sugar, and Dijon mustard until smooth and fully combined.
- Brush or pour the glaze over the top and sides of the meatloaf, ensuring it is evenly coated.
- Bake the Meatloaf:
- Place the baking sheet in the preheated oven and bake for 1 hour. Begin checking the internal temperature using a meat thermometer after the first hour.
- Continue baking as needed, checking every 5 to 10 minutes, until the internal temperature reaches 155°F (68°C).
- Once cooked, carefully remove the meatloaf from the oven and let it rest for 5 minutes on the baking sheet.
- Slice the meatloaf into 8 even portions and serve with your favorite sides.

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